Objectives: -Review why, for what, and how ultrasound is used in hidradenitis suppurativa

Disclosures

Did you receive any funding to support your research for this TOPIC?
No

Were you provided with any honoraria, payment or other compensation for your work on this study?
No

Do you have any financial relationship with any entity which may closely compete with the medications, materials or instruments covered by your study?
No

Do you own or have you applied for any patents in conjunction with the instruments, medications or materials discussed in your study?
No

This work is presented thanks to the support of: Springer by victor

Disclosures

Did you receive any funding to support your research for this TOPIC?
No

Were you provided with any honoraria, payment or other compensation for your work on this study?
No

Do you have any financial relationship with any entity which may closely compete with the medications, materials or instruments covered by your study?
No

Do you own or have you applied for any patents in conjunction with the instruments, medications or materials discussed in your study?
No

This work was not supported by any direct or non direct funding. It is under the author's own responsability

Objectives: HS is a chronic, recurrent skin inflammatory disease associated with significant psychological burden, like reduced QoL, depression, anxiety, and sexual dysfunction.
Important comorbidities include working disability, metabolic syndrome, inflammatory bowel disease and axial spondyloarthritis.
HS patients are at higher risk of cardiovascular death and suicide risk.
The aim of this presentation is to learn appropriate screening in daily clinical practice for early identification and evidence based treatment of HS comorbidities.

Conclusion: HS has a great impact on patients
It has been associated with several comorbidities, some of them asymptomatic.
HS patients are at risk of cardiovascular death
Psychological distress in patients with HS must be addressed by us
Appropriate screening should be implemented in daily clinical practice.

Disclosures

Did you receive any funding to support your research for this TOPIC?
No

Were you provided with any honoraria, payment or other compensation for your work on this study?
No

Do you have any financial relationship with any entity which may closely compete with the medications, materials or instruments covered by your study?
No

Do you own or have you applied for any patents in conjunction with the instruments, medications or materials discussed in your study?
No

This work was not supported by any direct or non direct funding. It is under the author's own responsability

Objectives: The challenges in managing Hidradenitis suppurativa(HS) and the substantial disease burden for patients and the health system have recently gained attention.
According to the VOICE project, a multinational survey among 1,299 participants, 45.9% of HS-patients are dissatisfied or very dissatisfied with care, even though they mainly received treatment according to current guidelines (mostly oral antibiotics, 85.6%).While HS was in the past mainly treated surgically in the stationary setting, it is now increasingly becoming relevant for outpatient care due to the increasing therapeutic options.

Materials / method: The literature was screened for all therapies approved for the indication of HS since the publication of the European guidelines in 2015. Moreover, all drug-option for HS currently undergoing phase-III-trials were identified from the database of clinicaltrials.gov

Results: A new device-based therapy option, combining intense pulsed light and radiofrequency, was approved for HS which shows good results in two randomized controlled trials and case reports and can be applied as long-term treatment. Clinicaltrials.gov showed that Secukinumab and Bimekizumab as well as Povorcitinib and Metformin are currently in the stage of phase-III trials. While results of the completed Bimekizumab trial are not published yet, the placebo-controlled trials on Secukinumab have recently been completed with HiSCR-response approximately 10% lower than that of Adalimumab.

Conclusion: The therapy repertoire for HS is currently subject to rapid development. Besides the expected future availability of additional biologics and small molecules, especially the device-based therapy option combining intense pulsed light and radiofrequency shows promising results mainly in the treatment of Hurley I and II. This enables doctors in outpatient care to design efficient individualized long-term treatment plans for their HS-patients.

Disclosures

Did you receive any funding to support your research for this TOPIC?
No

Were you provided with any honoraria, payment or other compensation for your work on this study?
No

Do you have any financial relationship with any entity which may closely compete with the medications, materials or instruments covered by your study?
No

Do you own or have you applied for any patents in conjunction with the instruments, medications or materials discussed in your study?
No

This work was not supported by any direct or non direct funding. It is under the author's own responsability