Objectives: How to avoid complications and how to treat them
Introduction: A 62-year-old patient presented ischemia of the right dominant arm and hand after being injected with hyaluronic acid in an upper arm crease. Occlusion of the radial artery, the deep and superficial palmar arch and the common digital arteries, as well as the princeps pollicis artery, was caused by an accidental injection of HA into the brachial artery.
Materials / method: The patient was treated with a catheter-delivered injection of high dose (4.500 units) off- label hyaluronidase into the ulnar and radial artery and additional subcutaneous hyaluronidase application (1500 units) to the forearm and hand. In addition, a plexus catheter was placed 24 hours after initial treatment to achieve sympatholysis and promote vasodilatation. After a second intraarterial hyaluronidase injection (1500 units) combined with lysis therapy via alteplase and adjuvant hyperbaric oxygen therapy.
Results: Full revascularization of the right upper extremity was achieved.
Conclusion: We conclude that off-label treatment with high dose intra-arterial hyaluronidase led to successful restoration of blood circulation after vascular occlusion due to intraarterial HA injection.
Disclosures
Did you receive any funding to support your research for this TOPIC?
No
Were you provided with any honoraria, payment or other compensation for your work on this study?
No
Do you have any financial relationship with any entity which may closely compete with the medications, materials or instruments covered by your study?
No
Do you own or have you applied for any patents in conjunction with the instruments, medications or materials discussed in your study?
No
This work was not supported by any direct or non direct funding. It is under the author's own responsability