Objectives: There are various skin booster in the aesthetic fields and should understand between collagen synthesis and fibrosis. Skin booster injection is very much related to facial layers.

Introduction: There are various biostimulators in aesthetic market and the mechanism is related with fibroblast activation and macrophage modulation.

Materials / method: We will overview the proposed mechanism of biostimulators and facial layer relationship which dermal activation and subcutaneous reaction of foreign body reaction.

Results: Dermis is the key point for biostimulation and multiple injection methods are proposed for proper injection.
Subcutaneous injection are made by biostimulators and fibrosis study should be made.

Conclusion: Proper use of biostimulation is needed. Not all the mechanism are same for various biostimulations

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Objectives: The pursuit of natural-looking lip enhancement has gained significant attention, particularly among Asian patients who often prefer subtle, harmonious results. This study explores the combined use of lip fillers and thread lifting techniques to achieve a balanced and natural appearance. Lip fillers provide volume and hydration, while threads enhance definition and lift, addressing unique anatomical considerations in Asian lips. By leveraging the complementary benefits of both procedures, practitioners can achieve tailored outcomes that respect cultural aesthetics and individual prefer